Patellar resurfacing in total knee replacement: 20-year clinical and economic results of a large multicentre, randomised controlled trial in the UK.

この研究はインパクトが大きい可能性があると判断されました。 OEのAIによるハイインパクト指標は、論文が掲載されたジャーナルと論文自体の科学的内容の両方からのシグナルを統合することで、論文の影響力を推定します。 最先端の自然言語処理を用いて開発されたOEハイインパクトモデルは、ジャーナルのインパクトファクターのみよりも、研究の将来の引用実績をより正確に予測します。 これにより、臨床的に意義のある研究をより早く認識することができ、読者は将来の診療を形成する可能性が最も高い論文に焦点を当てることができます。

研究概要

1715 patients undergoing primary total knee replacement (TKR) were randomized to receive patellar resurfacing or no patellar resurfacing. The primary clinical outcome was the Oxford Knee Score (OKS), while the primary economic outcome was incremental cost per quality-adjusted life-year gained. Secondary outcomes included the 12-Item Short Form Health Survey (SF-12), European Quality of Life 5-Dimensions 3-Levels score (EQ-5D-3L), reoperations, complications, health-care costs, and mortality. Outcomes were assessed at 3 months, 1 year, and annually for up to 20 years. Overall, the results revealed no statistically significant difference in OKS or other clinical outcomes, although most estimates numerically favoured patellar resurfacing. Patellar resurfacing produced significantly more quality-adjusted life-years without increasing overall 20-year health-care costs, suggesting that it is likely the preferred and more cost-effective strategy.