Showing 1 - 12 of 377 reports matching: Osteoarthritis
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Synopsis: 7 randomized controlled trials (RCTs) were included in this systematic review and meta-analysis comparing conservative treatment methods of intra-articular hyaluronic acid injections and corticosteroid injections. Pain scores were pooled at 2, 4, 8, 12, and 26 weeks post-injection. At early follow-up Read More »
Level 1 Meta Analysis
Synopsis: 63 randomised placebo-controlled trials were included in this meta-analysis to determine the maximal short-term effect of common pharmacotherapeutic interventions for short-term pain relief for knee osteoarthritis. Opioid therapy, oral NSAID, topical NSAID, steroid injections, paracetamol, glucosamine sulphate, and chondroitin sulphate were evaluated in this study. When assessed in Read More »
Level 2 Meta Analysis
Synopsis: Ten randomized controlled trials were included in this meta-analysis to evaluate the efficacy of intra-articular corticosteroid injections compared to placebo for the management of knee osteoarthritis. A dichotomous outcome of symptom improvement, defined as the most important patient-oriented outcome, and pain outcome were evaluated. Corticosteroid injections resulted Read More »
Level 2 Meta Analysis
Synopsis: Five randomized controlled trials were included in this meta-analysis to evaluate the efficacy of intra-articular corticosteroid injections compared to placebo in patients with knee osteoarthritis. The outcomes of interest that were pooled using meta-analysis were a failure to reach a target pain outcome and pain scores on a visual analog scale (VAS). Significantly fewer patients Read More »
Level 2 Meta Analysis
Synopsis: 29 out of 40 patients with osteoarthritis of the knee exhibited impaired conditioned pain modulation (CPM) and were randomized to one of two interventions (with cross-over thereafter) for the purpose of examining physiotherapeutic effects on knee pain, pressure pain thresholds, and vibration perception thresholds: (1) oscillatory joint mobilization or (2) cutaneous input (control -light placement of both hands on the subject's knee). Results demonstrated that Read More »
Author verified Level 2 RCT
Synopsis: 147 patients with advanced osteoarthritis of the knee or hip who were eligible for total knee arthroplasty (TKA) or total hip arthroplasty (THA) were randomized to receive two modes of patient decision-making tools for the purpose of comparing differences in patient knowledge, decision-making participation, satisfaction, and treatment preferences: (1) Educational DVD and booklet, or (2) Educational booklet only. When assessed at four weeks, both groups resulted in satisfactory improvements in various decision-aid related outcomes, such as patient knowledge score, confidence in decision making, and satisfaction with the intervention, however, the decision aids did not affect the willingness to participate in OA management. There were no Read More »
Level 2 RCT
Synopsis: 12 patients with bilateral knee osteoarthritis had one knee randomized to injection with 20mg triamcinolone hexacetonide, and the other knee randomized to injection with saline. The purpose of this study was to compare pain, knee stiffness & tenderness, patient preference, and thermographic indices between knees over a 6-week follow-up. While reporting of Read More »
Level 2 RCT
Synopsis: 16 patients (24 knees) with knee osteoarthritis were randomized to an injection with either 20mg triamcinolone hexacetonide or placebo. After 1 week, patients initially administered a triamcinolone hexacetonide injection received a saline injection, and patients initially administered a saline injection received a triamcinolone hexacetonide injection. Patients were assessed Read More »
Level 2 RCT
Synopsis: 77 patients with knee osteoarthritis underwent knee arthroscopy & joint lavage, followed by an intra-articular injection of corticosteroid (120mg methylprednisolone acetate) or placebo saline, assigned randomly. The outcomes assessed included patient-reported pain and function, response rate (minimum 30% reduction in pain from baseline), and relapse rate at 2, 4, 8, 12, and 24-week follow-ups. Results demonstrated no Read More »
Level 2 RCT
Synopsis: 25 patients with a total of 38 knees with osteoarthritis were randomized to the order in which they received either hydrocortisone tert-butylacetate, hydrocortisone acetate, or placebo injections. For each treatment, four injections were given, every 2 weeks. A washout period Read More »
Level 2 RCT
Synopsis: 120 patients with knee osteoarthritis were randomized to a single intra-articular injection of either 40mg triamcinolone acetate, 3mg betamethasone disodium phosphate, 40mg methylprednisolone acetate or placebo. Patients were followed at 1, 3, 6, and 12 weeks after injection for pain reduction on a visual analog scale and functional improvement on the Lequesne Functional Index. Results demonstrated significantly Read More »
Level 2 RCT
Synopsis: 62 patients with medial knee osteoarthritis or osteonecrosis who were scheduled for opening-wedge high tibial osteotomy were randomized to the procedure using either combined CT-based and image-free navigation technology or conventional techniques to create the correction angle. The primary purpose of this study was to evaluate if navigation allowed for fewer coronal and sagittal outliers on postoperative computed tomography (CT). No significant difference Read More »
Level 2 RCT