Showing 1 - 12 of 400 reports matching: Spine
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Synopsis: 12 randomized controlled trials were included in this meta-analysis for the purpose of investigating potential differences in reoperation rates following anterior cervical discectomy and fusion (ACDF) and cervical disc arthroplasty (CDA) at the index level and/or adjacent levels for patients with cervical spondylosis. Results demonstrated that patients who underwent CDA required significantly fewer reoperations at the index level, the adjacent levels, or at either level type when compared to patients who received ACDF up to seven years post-surgery. However, due to Read More »
Level 1 Meta Analysis
Synopsis: 90 patients with thoracolumbar fractures were randomized to receive one of three surgical interventions: three-level percutaneous fixation, two-level percutaneous fixation, or three-level open fixation. The purpose of this study was to compare clinical and radiological outcomes of these three procedures after a mean follow-up of 17.7 months. Results demonstrated comparable Read More »
Level 2 RCT
Synopsis: 99 patients with lumbar facet joint syndrome were randomized to one of three study groups for the purpose of comparing the efficacy of pain and disability relief throughout a 12-week observational period: (1) combination of methylprednisolone injection and oral diclofenac, (2) methylprednisolone injection alone, or (3) oral diclofenac alone. Results demonstrated that Read More »
Level 2 RCT
Synopsis: 80 patients with symptomatic lumbar 4-5 stenosis undergoing posterior lumbar interbody fusion (PLIF) were randomized to receive either preemptive multimodal analgesia (celecoxib, pregabalin, oxycodone ER, and acetaminophen) or standard postoperative intravenous morphine. The purpose of this study was to compare pain in the immediate postoperative period and radiographic outcome up to one year after surgery. Results demonstrated significantly Read More »
Level 2 RCT
Synopsis: 378 patients with non-specific low back pain (LBP) were randomized to 3 groups: paraspinous lidocaine injection, analgesics, and exercise (Lidocaine group); sham paraspinous lidocaine injection, analgesics, and exercise (Sham group); or analgesics and exercise (Standard treatment group). The purpose of this study was to determine the efficacy of these combination treatments in the reduction of pain and improvement of function after a 3-month follow-up. Findings indicated significantly Read More »
Level 2 RCT
Synopsis: 62 patients with bi-segmental degenerative disc disease at L4-S1 were randomized to receive either hybrid anterior lumbar interbody fusion (ALIF) at L5/S1 with total disc replacement (TDR) at L4/5 or conventional 2-level circumferential fusion with transforaminal lumbar interbody fusion (TLIF) for the purpose of comparing pain and radiographic parameters throughout a 37-month follow-up period. Results demonstrated that patients in the Hybrid group had significantly reduced pain scores when compared to the Fusion group at both the 1-week and 37-month follow-up points. Additionally, significant increases Read More »
Level 2 RCT
Synopsis: 51 patients with T11-L2 thoracolumbar burst fractures (TCBF) were randomized to receive either single screw-rod anterior instrumentation (SSRAI) or double screw-rod anterior instrumentation (DSRAI). The purpose of this study was to compare the two instrumentation techniques to determine their comparative clinical efficacy on TCBFs with incomplete neurological deficit. Findings indicated no Read More »
Level 2 RCT
Synopsis: 94 patients undergoing lumbar interbody fusion for spinal stenosis were randomized to receive postoperative pain control via either a conventional intravenous patient-controlled analgesia (PCA) pump or a continuous epidural catheter administration of 0.2% ropivacaine. The purpose of this study was to determine if the use of a continuous epidural reduced postoperative pain, use of opioids, the length of hospital stay, and the incidence of adverse events when compared to standard PCA. The results demonstrated Read More »
Level 2 RCT
Synopsis: 73 adult patients with isthmic spondylolisthesis were randomized to be treated with either the posterior lumbar interbody fusion technique (PLIF) or the transforaminal lumbar interbody fusion (TLIF) technique. The purpose of this study was to compare the two methods in their clinical and radiographic outcomes over a 2-4 year follow-up. While results demonstrated Read More »
Level 2 RCT
Synopsis: 12 adolescents with idiopathic scoliosis were included in this pilot study and randomized to receive either continuous infusion of anesthetic (0.25% levobupivacaine) or saline at the iliac crest bone graft (ICBG) donor site for the purpose of assessing effect on postoperative donor site pain, overall pain, potential donor site complication, and adverse effects throughout a five-day post-surgery period. Results demonstrated a decrease in ipsilateral and contralateral iliac crest pain between groups, favouring the local anesthetic group, however, the statistical significance of this difference was not reported. An additional large-scale Read More »
Level 2 RCT
Synopsis: 10 studies (6 RCTs) were included in this meta-analysis for the purpose of determining whether or not platelet concentrates are able to enhance union rates and reduce overall complications in patients undergoing fusion for degenerative and traumatic etiologies. Pooled results indicated that the use of platelet concentrates resulted in a significantly decreased union rate compared to control groups. Additionally, total complication Read More »
Author verified Level 2 Meta Analysis
Synopsis: 599 patients with either single- or two-level degenerative cervical disc disease were randomized to treatment through either cervical disc arthroplasty (CDA) or anterior cervical discectomy and fusion (ACDF). Data on subsequent surgeries - occurring either at the index level, adjacent level, or both - were obtained and compared between groups. Data demonstrated significantly Read More »
Author verified Level 2 RCT