Showing 1 - 12 of 406 reports matching: Spine
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Synopsis: 40 patients with adolescent idiopathic scoliosis were randomized to have a computer-aided design and manufactured thoraco-lumbo-sacral orthosis with or without the addition of finite element simulation during the design process. Patients underwent radiographic evaluation during brace wearing to assess correction in thoracic and lumbar Cobb angle, as well as thoracic kyphosis and lumbar lordosis angles. Results demonstrated a Read More »
Level 2 RCT
Synopsis: 90 patients with degenerative spinal disorders undergoing lumbar spinal fusion were randomized to receive either cognitive-behavioural therapy or standard treatment. The objective of this study was to determine whether or not cognitive-behavioural therapy (CBT) has the ability to affect early postoperative outcomes such as back pain, mobility, analgesic consumption, and hospital stay duration. Findings indicated no Read More »
Level 2 RCT
Synopsis: 107 patients with single-level cervical spondylosis were randomized to undergo either cervical disc arthroplasty (CDA) with the Mobi-C Cervical Disc Prosthesis or ACDF. The purpose of this study was to compare patient-reported outcome measures, the radiographic range of motion of the index segment, and subsequent surgery rates between groups. At 5 year Read More »
Level 2 RCT
Synopsis: 40 patients with low back pain due to sacroiliac joint arthritis were randomized to receive a singular steroid/anesthetic injection with the aid of either ultrasound or fluoroscopic guidance. The purpose of this study was to compare differences in efficacy (pain, disability), accuracy (intraarticular vs. periarticular needle placements), and patient discomfort/satisfaction throughout three-month follow-up. Results demonstrated that Read More »
Level 2 RCT
Synopsis: 389 patients with moderate-to-severe chronic low back pain (LBP) were randomized to receive one of five dose-ranging subcutaneous injection treatments: 1mg fulranumab every 4 weeks, 3mg fulranumab every 4 weeks, 3mg fulranumab every 4 weeks after a 6mg loading dose, 10mg fulranumab every 4 weeks, or placebo every 4 weeks. The purpose of this study was to determine the efficacy and safety of fulranumab compared to placebo in terms of the LBP numeric rating scale for pain intensity, Oswestry Disability Index scores, Brief Pain Inventory pain intensity and interference scores and treatment relief, and patient global assessment scores. Outcomes were measured Read More »
Level 2 RCT
Synopsis: 97 patients scheduled for posterior lumbar interbody fusion were randomized to postoperative analgesia through one of three groups: pregabalin 75mg, pregabalin 150mg, or diazepam 5mg as an active placebo. The purpose of this study was to determine the analgesic efficacy of the two pregabalin doses. Pain scores and Read More »
Level 2 RCT
Synopsis: 12 randomized controlled trials were included in this meta-analysis for the purpose of investigating potential differences in reoperation rates following anterior cervical discectomy and fusion (ACDF) and cervical disc arthroplasty (CDA) at the index level and/or adjacent levels for patients with cervical spondylosis. Results demonstrated that patients who underwent CDA required significantly fewer reoperations at the index level, the adjacent levels, or at either level type when compared to patients who received ACDF up to seven years post-surgery. However, due to Read More »
Level 1 Meta Analysis
Synopsis: 90 patients with thoracolumbar fractures were randomized to receive one of three surgical interventions: three-level percutaneous fixation, two-level percutaneous fixation, or three-level open fixation. The purpose of this study was to compare clinical and radiological outcomes of these three procedures after a mean follow-up of 17.7 months. Results demonstrated comparable Read More »
Level 2 RCT
Synopsis: 99 patients with lumbar facet joint syndrome were randomized to one of three study groups for the purpose of comparing the efficacy of pain and disability relief throughout a 12-week observational period: (1) combination of methylprednisolone injection and oral diclofenac, (2) methylprednisolone injection alone, or (3) oral diclofenac alone. Results demonstrated that Read More »
Level 2 RCT
Synopsis: 80 patients with symptomatic lumbar 4-5 stenosis undergoing posterior lumbar interbody fusion (PLIF) were randomized to receive either preemptive multimodal analgesia (celecoxib, pregabalin, oxycodone ER, and acetaminophen) or standard postoperative intravenous morphine. The purpose of this study was to compare pain in the immediate postoperative period and radiographic outcome up to one year after surgery. Results demonstrated significantly Read More »
Level 2 RCT
Synopsis: 378 patients with non-specific low back pain (LBP) were randomized to 3 groups: paraspinous lidocaine injection, analgesics, and exercise (Lidocaine group); sham paraspinous lidocaine injection, analgesics, and exercise (Sham group); or analgesics and exercise (Standard treatment group). The purpose of this study was to determine the efficacy of these combination treatments in the reduction of pain and improvement of function after a 3-month follow-up. Findings indicated significantly Read More »
Level 2 RCT
Synopsis: 62 patients with bi-segmental degenerative disc disease at L4-S1 were randomized to receive either hybrid anterior lumbar interbody fusion (ALIF) at L5/S1 with total disc replacement (TDR) at L4/5 or conventional 2-level circumferential fusion with transforaminal lumbar interbody fusion (TLIF) for the purpose of comparing pain and radiographic parameters throughout a 37-month follow-up period. Results demonstrated that patients in the Hybrid group had significantly reduced pain scores when compared to the Fusion group at both the 1-week and 37-month follow-up points. Additionally, significant increases Read More »
Level 2 RCT