Showing 1 - 12 of 352 reports matching: Osteoarthritis
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Synopsis: 34 women with osteoarthritis of the knee were randomized to a six-week physiotherapy regimen consisting of either low-load exercises with partial vascular occlusion (PVO) or conventional high-load exercises (without PVO). The purpose of this study was to determine if occluded, low-load quadriceps muscle exercise were associated with similar improvements in pain, function, and knee performance when compared to conventional therapy. Results demonstrated that Read More »
Level 2 RCT
Synopsis: 50 patients with knee primary osteoarthritis were randomly assigned to receive orally administered 180 mg/day curcumin (Theracurmin) or placebo for 8 weeks. The purpose of this trial was to determine the effects of curcumin in patients with knee osteoarthritis via blood biochemistry analyses, VAS pain, Japanese Knee Osteoarthritis Measure, Japanese Orthopedic Association knee scoring system, need for nonsteroidal anti-inflammatory drugs (NSAIDs), and adverse events. The findings revealed Read More »
Level 2 RCT
Synopsis: 100 patients with knee osteoarthritis were randomized to receive physical therapy with either an intra-articular (IA) corticosteroid injection of 1mL methylprednisolone (40mg DepoMedrol, Pfizer) dissolved in 4mL lidocaine (10mg/mL, SAD), or an IA placebo injection of 1mL isotonic saline with 4mL lidocaine (10mg/mL, SAD). The purpose of this study was to determine whether an IA corticosteroid injection in combination with physical therapy is able to improve ultrasound-assessed signs of inflammation such as synovial hypertrophy, Doppler activity, and Baker's cyst presence after 12 weeks of treatment. Findings indicated comparable Read More »
Level 1 RCT
Synopsis: 60 patients with a clinical diagnosis of tibiofemoral osteoarthritis were randomized to enter a 12-week exercise regimen or remain sedentary for the study duration. The purpose of this study was to quantify the effectiveness of therapeutic exercise as a conservative treatment of osteoarthritic pain and function. Pressure-pain thresholds and Read More »
Level 2 RCT
Synopsis: 102 patients with first metatarsophalangeal (MTP) joint osteoarthritis (OA) were randomized to receive individualized, prefabricated foot orthoses or rocker-sole footwear. The purpose of this study was to compare the orthoses and footwear to determine their effects on pain reduction. Findings indicated no Read More »
Author verified Level 2 RCT
Synopsis: 4 randomized controlled trials (n=1833 patients) were included in this meta-analysis for the purpose of comparing analgesic efficacy and safety of tanezumab when compared to placebo treatment. Outcomes of interest included changes in Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain, WOMAC physical function, patient global assessment, the incidence of adverse events, and treatment discontinuation due to adverse effects. Results demonstrated that Read More »
Level 1 Meta Analysis
Synopsis: 9 randomized controlled trials (n= 696 patients) of low to moderate quality were included in this systematic review and meta-analysis to determine the effects of isokinetic muscle strengthening on pain, function, and disability in patients with knee osteoarthritis when compared to another isokinetic muscle strengthening treatment, another muscle reinforcement treatment, or no treatment. Data of the following outcomes were available for meta-analysis: standing pain, Lequesne index for function, WOMAC index, and ambulation speed. Findings indicated significant Read More »
Level 2 Meta Analysis
Synopsis: 4 RCTs were included in this meta-analysis and systematic review for the purpose of comparing effects on quadriceps muscle strength after exercise therapy with and without whole-body vibration. Results demonstrated that Read More »
Level 1 Meta Analysis
Synopsis: 109 patients with hip osteoarthritis (OA) were randomized to receive either a combination therapy of physical exercise and patient education or a control group of patient education alone. The purpose of this study was to compare the long-term effects of these treatments on secondary outcome measures including the range of motion (ROM), muscle strength, predicted maximal oxygen consumption, walking distance, and pain during walking. Outcomes were assessed Read More »
Level 2 RCT
Synopsis: 40 patients with hip osteoarthritis undergoing total hip replacement were included in this trial to determine the effectiveness of occupation therapy supervised usage of adaptive devices. Patients were randomized to an experimental group that used adaptive devices in an organized and supervised manner or to a control group that used devices without supervision. Devices included abduction Read More »
Author verified Level 2 RCT
Synopsis: 164 patients with knee osteoarthritis (OA) were randomized to wear either unloading walking shoes or conventional walking shoes, to be worn for at least 4 hours per day for a duration of 6 months. The purpose of this study was to determine whether the use of unloading walking shoes was able to reduce pain and improve physical functioning compared to conventional walking shoes in patients with knee OA. Findings indicated no Read More »
Author verified Level 2 RCT
Synopsis: 70 patients with knee osteoarthritis (Kellgren-Lawrence grades 2-4) were randomized to treatment with either a transcutaneous electrical nerve stimulation (TENS) knee brace for 3 months or standard of care. Patients were followed up for a minimum of 1-year, evaluating pain, function, and health-related quality of life. Results demonstrated no Read More »
Level 2 RCT