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Denosumab and teriparatide significantly improves BMD in patients with osteoporosis

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Ace Report Cover
July 2014

Denosumab and teriparatide significantly improves BMD in patients with osteoporosis

Vol: 3| Issue: 7| Number:56| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Two Years of Denosumab and Teriparatide Administration in Postmenopausal Women With Osteoporosis (The DATA Extension Study): A Randomized Controlled Trial

J Clin Endocrinol Metab. 2014 May;99(5):1694-700

Contributing Authors:
BZ Leder JN Tsai AV Uihlein SA Burnett-Bowie Y Zhu K Foley H Lee RM Neer

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Synopsis

94 postmenopausal women, >45 years of age, who had been diagnosed with osteoporosis and who were at high risk for fracture, were randomly assigned into 1 of 3 treatment groups to determine the long term effect (24 months) a combination of denosumab and teriparatide had on hip and spine BMD. Patients either received a combined drug treatment of denosumab and teriparatide, or intervention with denos...

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