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Efficacy of ketamine, pregabalin, and combined analgesia in total hip arthroplasty

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Ace Report Cover
April 2014

Efficacy of ketamine, pregabalin, and combined analgesia in total hip arthroplasty

Vol: 3| Issue: 4| Number:56| ISSN#: 2564-2537
Study Type:Randomized Trial
OE Level Evidence:1
Journal Level of Evidence:N/A

The analgesic efficiency of combined pregabalin and ketamine for total hip arthroplasty: a randomised, double-blind, controlled study

Anaesthesia. 2014 Jan;69(1):46-52

Contributing Authors:
V Martinez A Cymerman S Ben Ammar JF Fiaud C Rapon F Poindessous T Judet M Chauvin D Bouhassira D Sessler X Mazoit D Fletcher

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Synopsis

142 patients scheduled for total hip arthroplasty were randomized to receive treatment with ketamine infusion during anaesthesia, preoperative oral pregabalin, combined ketamine and pregabalin, or placebo of both. The purpose was to determine if the combination of drugs was more efficacious than either alone. All patients received patient-controlled morphine analgesia postoperatively, and were eva...

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