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We found 2077 reports published by T (Newest First)

AAOS: Pinless computer navigation system more accurate than conventional technique in TKA

100 patients scheduled to undergo primary total knee arthroplasty (TKA) were randomized to undergo the procedure using either a new pinless computer navigation system or a conventional technique. The purpose of this study was to examine the accuracy of this new system for implant alignment. Results indicated that there was a significant difference ...

AAOS: Superior outcome when elbow rotation is delayed following radial head fracture

300 patients with radial head fractures were randomized to receive a mobilization protocol with either early or delayed active elbow rotation. The purpose was to determine whether the difference in timing has an effect on clinical outcome after 2 years. Result indicated that patients with delayed elbow rotation enjoyed significantly better Broberg-...

AAOS: Triclosan-coated sutures do not reduce surgical site infection following THA & TKA

2547 patients undergoing total knee or hip arthroplasty were randomly allocated to receive triclosan-coated sutures or standard sutures for layered wound closure, with the purpose of determining if triclosan-coated sutures could reduce the incidence of surgical site infection. Results did not support the use of triclosan-coated sutures, as there wa...

AAOS: A combination of two prep solutions prevents infection regardless of order applied

95 patients undergoing foot and ankle surgery were randomized to receive either 4% chlorhexidine gluconate followed by 70% isopropyl alcohol while preparing the surgical site, or the same two solutions applied in a reverse order. The purpose of this study was to determine whether the order of application of these two solutions has an effect on bact...

AAOS: Pronator quadratus repair following volar plate fixation offers no clinical benefit

60 patients with distal radius fractures were randomly allocated to undergo volar plate fixation with or without pronator quadratus (PQ) muscle repair following the procedure, to determine whether PQ repair improves wrist function and other clinical outcomes. Results indicated that PQ repair did not improve wrist function or pain at 12 months post-...

AAOS: Blood loss and transfusion rates do not differ between tranexamic acid preperations

60 patients undergoing total hip arthroplasty were randomized to receive intravenous or topical tranexamic acid to compare the efficacy of preparations on postoperative blood loss and transfusion rates. Results indicated blood loss, change in hemoglobin levels, transfusion rates, and thromboembolic events did not differ significantly between groups...

AAOS: Quantitative ultrasound can detect the effects of risendronate on bone strength

138 women (100 at final follow-up) who underwent short proximal femoral nailing for a low-energy intertrochanteric fracture were randomized to receive either risendronate (75 mg twice monthly) or a placebo equivalent. The purpose of this study was to examine whether quantitative ultrasound was able to detect the effects of risendronate on bone stre...

AAOS: Time to ambulation without any assistive device is improved with direct anterior THA

54 patients were randomly allocated to receive a direct anterior or mini-incision posterior approach to total hip arthroplasty (THA), to determine if there were differences in time to ambulation between the two techniques. Results indicated that time to ambulation without any assistive device was significantly improved with direct anterior total h...

AAOS: Operative versus nonoperative management of Achilles tendon ruptures

Seven randomized controlled trials evaluating operative and nonoperative management of Achilles tendon ruptures were included in this meta-analysis. The purpose was to determine if the two treatment options differed in functional outcome over 2 years postintervention. The results indicated that while functional outcome was significantly better foll...

AAOS: Early rehabilitation acceptable following fixation of unstable ankle fracture

110 patients undergoing fixation of an unstable ankle fracture were randomized to either early weightbeaing (2 weeks postop) or delayed weightbearing (6 weeks non-weightbeaing and immobilization postop). The purpose was to compare the two protocols on rate of return to work and functional outcome. The results indicated that return to work was simil...

AAOS: Repeat skin antisepsis reduces incidence of surgical site infections after TJA

581 patients undergoing total joint arthroplasty (TJA) were randomized to receive standard or repeat preoperative skin antisepsis, to determine if repeat skin antisepsis is a beneficial addition to standard skin preparation. Results indicated that repeat skin antisepsis before incise draping significantly reduced surgical site infections compared t...

AAOS: Weightbearing-as-tolerated safe in rehabilitation following tibial shaft fractures

62 patients undergoing intramedullary nailing for tibial shaft fractures were randomized to postoperative protocols of either immediate weightbearing-as-tolerated (WBAT) or non-weightbearing (NWB) for 6 weeks postoperatively. Functional and radiographic outcomes were monitored up to fracture union, or until treatment failure or revision surgery was...

AAOS: Autologous chondrocyte implantation vs microfracture for articular cartilage lesions

50 patients with articular cartilage lesions were randomized to treatment with either mircrofracture surgery or all-arthroscopic matrix encapsulated autologous chondrocyte implantation (MECI). The purpose was to compare the clinical and morphological outcomes between techniques following repair. Results up to 2 years postoperative revealed better T...

AAOS: Hyaluronic acid and placebo produce similar pain and functional outcomes for knee OA

200 patients suffering from mild to moderate knee osteoarthritis were randomly allocated to receive 3 hyaluronic acid (HA) injections or 3 placebo injections to determine the ability of HA to improve knee pain and function. A Visual Analog Scale (VAS) for pain, the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), knee range o...

AAOS: Complication rate lower with bone tunnels in repair of distal biceps tendon ruptures

23 studies (randomized controlled trials, prospective cohort studies, and retrospective case series) were included in this literature review comparing surgical approaches and fixation methods in operative management of distal biceps tendon ruptures. The results indicated that the overall complication rate among all studies was 24.7%, with no signif...

AAOS: Efficacy of BMP in expedited union continues to be debated

19 studies (12 RCTs, 6 prospective cohorts, 3 retrospective cohorts) were included in this investigation on the efficacy of BMP-2 and BMP-7 in bony healing following acute fracture or nonunion. The results indicated that there was no significant difference between BMP and non-BMP-treated groups regarding union rate of healing time following treatme...

AAOS: Medial parapatellar arthrotomy VS quadriceps-sparing subvastus approach for TKA

128 patients were randomly allocated to undergo a medial parapatellar arthrotomy or quadriceps-sparing approach to total knee arthroplasty (TKA), to determine if one technique provided superior early functional outcomes. To accurately compare results, both approaches used minimally invasive surgical principles. Short-term results revealed no statis...

AAOS: Lower graft failure with autograft vs. allograft ACL reconstruction at min. 10 years

100 knees from 99 patients were randomized to ACL reconstruction with the use of either autografts or allografts. The purpose of this study was to assess and compare the long-term results of the aforementioned interventions. Results at a minimum of 10 years revealed over 80% success rates and similar single assessment numeric evaluations. However, ...

AAOS: Superior functional outcome with arthroscopic versus open Bankart repair

38 patients with anterior glenohumeral joint dislocation schedule for Bankart repair were randomized to receive either open Bankart repair or arthroscopic Bankart repair. The purpose of this study was to determine whether one method was more effective with respect to functional outcome and incidence of recurrent dislocations. Results from follow-up...

AAOS: Highly-porous-metal tibial components appear durable & reliable 5 years after TKA

389 patients undergoing total knee arthroplasty (TKA) were randomized to one of three groups: an uncemented highly-porous-metal tibial component group, a cemented highly-porous tibial component group, or a cemented traditional tibial component group. The purpose of this study was to compare the reliability and durability between treatment groups. U...

AAOS: Barbed sutures may be a plausible option for wound closure in TKA

411 patients undergoing total knee arthroplasty were randomized to receive barbed or standard sutures for wound closure, with the purpose of comparing overall efficiency and safety of both treatment options. Upon analysis, barbed sutures appeared to reduce closure times and costs compared to standard sutures, while postoperative complications, clin...

RCT2: Blood loss with 6h postop flexion after TKA lower than with 3h flexion or extension

420 patients scheduled for total knee arthroplasty were randomized to either positioning of the knee in 120 deg passive flexion for 3 hours postoperatively, the same flexion for 6 hours postoperatively, or in full passive extension postoperatively. The objective was to determine the effect of each protocol on postoperative blood loss, transfusion r...

Bone Joint J. 2014 Feb;96-B(2):201-9

Teriparatide increases hip & spine BMD, particularly in type I osteogenesis imperfecta

79 patients with osteogenesis imperfecta (OI) were randomized to receive either teriparatide (recombinant human parathyroid hormone) or a placebo administered subcutaneously daily for 18 months. The purpose of this proof-of-concept study was to determine whether teriparatide increased bone formation and positively affected skeletal mass and strengt...

J Clin Invest. 2014 Feb 3;124(2):491-8. doi: 10.1172/JCI71101.

An intra-articular injection of LMW human serum albumin is safe and effective for knee OA

329 patients with symptomatic knee osteoarthritis (OA) were randomized to receive either Low Molecular Weight Fraction of 5% human serum albumin (LMWF-5A) or saline vehicle solution, each at a dose of either 4 or 10 mL. The purpose of this study was to determine the analgesic efficacy and safety of LMWF-5A in this study population. Results indicate...

PLoS One. 2014 Feb 3;9(2):e87910. doi: 10.1371/journal.pone.0087910. eCollection 2014.

Pulsed electromagnetic field therapy improves pain, swelling, and function following TKA

33 patients scheduled for total knee arthroplasty for severe knee osteoarthritis were randomized to receive 60 days of pulsed electromagnetic field (PEMF) therapy after surgery, or to no additional postoperative PEMF. The purpose was to examine the effect of PEMF on pain, function, and swelling up to 6 months postoperatively. The results indicated ...

Int Orthop. 2014 Feb;38(2):397-403

Anterior cervical fixation with dynamic or rigid plating not significantly different

In this systematic review, seven studies were included (4 RCTs and 3 nonrandomized/retrospective studies) comparing the clinical and radiological outcomes between anterior cervical fixation with dynamic plates or rigid plates. Additionally, 4 studies were included in a complications analysis for dynamic plates (2 [1 RCT, 1 prospective nonrandomized...

Eur Spine J. 2014 Feb;23(2):298-304. doi: 10.1007/s00586-013-3039-3.

Fragility Index to aid in the interpretation of significant findings from RCTs

While P-values in clinical studies are an easy method to denote statistical significance, the interpretation of significant findings can be somewhat skewed. The Fragility Index is a newly developed metric that complements p-values and confidence intervals. It is calculated by adding consecutive events to a significant dichotomous finding until the ...

J Clin Epidemiol. 2014 Feb 5. pii: S0895-4356(13)00466-6. doi: 10.1016/j.jclinepi.2013.10.019

Multimodal analgesia is safer and more effective than PCA after minimally-invasive TKA

Thirty-six patients undergoing minimally-invasive total knee arthroplasty (TKA) desiring rapid recovery were randomized to follow either a multimodal analgesic protocol or patient-controlled analgesia (PCA) regimen, to compare the efficacy and safety of the two approaches. Results indicated that the use of a multimodal analgesic regimen led to sign...

J Arthroplasty. 2014 Feb;29(2):329-34. doi: 10.1016/j.arth.2013.06.005. Epub 2013 Jul 11.

Effect of HVLA vs. sham on vertical jump in athletes with talocrural joint dysfunction

22 female elite-level handball athletes with talocrural joint dysfunction were randomized to undergo high-velocity, low-amplitude (HVLA) manipulation to either the talocrural joint (active treatment) or the distal tibia (sham treatment). The purpose of this pilot study was to determine the feasibility of trial comparing these two interventions with...

J Manipulative Physiol Ther. 2014 Feb;37(2):116-23. doi: 10.1016/j.jmpt.2013.11.004. Epub 2014 Jan 2

Vertebral end-plate signal changes may not be the cause of disabling back pain in sciatica

Two hundred and sixty-three patients with sciatica were randomized to undergo either rapid surgical intervention, or prolonged conservative treatment. The dual purpose of this publication was (1) to compare the extent of vertebral end-plate signal changes (VESC) between groups, and (2) to determine whether or not there is a correlation between VESC...

Spine J. 2014 Feb 1;14(2):225-33. doi: 10.1016/j.spinee.2013.08.058. Epub 2013 Nov 13.

Shoulder impingement syndrome: treatment similar with & without neck mobilisation

Seventy-four patients with non-traumatic shoulder impingement syndrome were randomized to receive shoulder treatment either with or without neck mobilisation therapy. The purpose of this study was to determine whether the combined neck and shoulder treatment was more effective in improving pain and disability outcomes, measured with a NPRS and the ...

Man Ther. 2014 Feb;19(1):18-24. doi: 10.1016/j.math.2013.05.007.

Denosumab is superior to alendronate for improving cortical bone porosity post-menopause

Two hundred and forty-seven post-menopausal women (146 with data at final follow-up) received a subcutaneous injection every 6 months and a pill weekly. These treatments were randomized as follows: Group one received denosumab injections and a placebo pill, Group two received alendronate and a placebo injection and Group three received a placebo i...

Bone. 2014 Feb;59:173-9. doi: 10.1016/j.bone.2013.11.016. Epub 2013 Nov 22.

Active cranio-cervical flexion exercise can improve muscle control for chronic neck pain

Eighteen adults with chronic idiopathic neck pain were randomized to receive either assisted plus active cranio-cervical flexion (exercise group) or passive mobilisation plus assisted cranio-cervical flexion (mobilisation group). The purpose of the study was to determine which treatment was more efficacious with respect to performance on the cranio...

Man Ther. 2014 Feb;19(1):25-31. doi: 10.1016/j.math.2013.05.011.

TKA: Non-continuous drainage is equally safe, yet more effective than continuous drainage

9 randomized controlled trials (761 patients; 811 knees) comparing continuous with non-continuous drainage in total knee arthroplasty (TKA) were included in this review. The purpose of this review was to compare the efficacy and safety of these two techniques. Results indicated that non-continuous drainage significantly reduced haemoglobin loss and...

Int Orthop. 2014 Feb;38(2):361-71. doi: 10.1007/s00264-013-2105-0. Epub 2013 Sep 19.

Subluxation versus eversion of the patella in total knee arthroplasty

68 patients undergoing total knee arthroplasty were randomized to either patellar subluxation (retraction) or patellar eversion during surgery. The purpose was to determine if subluxation of the patella led to any benefit over eversion in outcome in the short- and medium-term. Follow-up was conducted for 1 year postoperatively. The results demonstr...

J Bone Joint Surg Am. 2014 Feb 5;96(3):207-13

PRP is effective in improving blood loss, pain and early functional outcomes following TKA

40 patients with knee arthritis (59 knees) undergoing either unilateral or bilateral total knee arthroplasty (TKA) were randomized to either receive or not receive an intraoperative injection of autologous platelet gel (APG). The purpose was to determine the effects of platelet-rich plasma (PRP) with respect to postoperative haemoglobin loss, pain ...

Int Orthop. 2014 Feb;38(2):387-95. doi: 10.1007/s00264-013-2136-6. Epub 2013 Oct 11.

Tight Calorie Control appears to reduce complication rates following hip fracture surgery

50 geriatric patients admitted to hospital after incurring a hip fracture were randomized to receive either a post-surgery tight calorie control meal plan, or a standard hospital meal plan. The primary aim of this study was to compare the length of hospital stay and presence of complications between the two groups. Upon analysis, tight calorie cont...

Clin Nutr. 2014 Feb;33(1):23-8. doi: 10.1016/j.clnu.2013.03.005. Epub 2013 Apr 1.

Minimally invasive longitudinal versus sinus tarsi approach for calcaneal fractures

167 patients with displaced intra-articular calcaneal fractures were randomized to surgery using either a minimally invasive longitudinal approach (MILA) or sinus tarsi approach (STA). The purpose was to compare functional and radiographic outcomes, as well as the incidence of complications. In Sanders type II and III fractures, the MILA was associ...

J Bone Joint Surg Am. 2014 Feb 19;96(4):302-9. doi: 10.2106/JBJS.L.01215

No effect of gentamicin in irrigation solution for reducing septic arthritis in ACLR

360 patients undergoing arthroscopic ACL reconstruction were randomized to receive saline irrigation fluid with or without the addition of gentamicin. The purpose was to compare these two treatment approaches with respect to rates of septic arthritis. Results indicated that although the rate of septic arthritis was higher in the saline group (2.2%)...

Arch Orthop Trauma Surg. 2014 Feb;134(2):257-61. doi: 10.1007/s00402-013-1910-7. Epub 2013 Dec 10

Pulsed electromagnetic field and exercise for SIS may improve pain and function

56 patients with shoulder impingement syndrome were randomized to receive treatment comprised of either 3-weeks of active pulsed electromagnetic field (PEMF) therapy or placebo PEMF, followed by a 6-week shoulder exercise program. The purpose was to evaluate the efficacy of PEMF in improving pain, function, and muscle strength. Results revealed tha...

Arch Phys Med Rehabil. 2014 Feb;95(2):345-52. doi: 10.1016/j.apmr.2013.09.022.

Portable device reduces number of outliers deviating from tibial component goals in TKA

100 patients scheduled for primary total knee arthroplasty were randomized to intraoperative placement of the tibial component using either a portable, accelerometer-based navigation device (KneeAlign, OrthoAlign, CA) or using conventional extramedullary guides. Radiographic outcome in patients was assessed at approximately 6 weeks post-surgery. Th...

J Arthroplasty. 2014 Feb;29(2):288-94

Decision support system reduces time to detect critical events in orthopaedic surgery

150 patients undergoing elective orthopaedic lower-limb surgery requiring spinal analgesia with propofol sedation were randomized to undergo the procedure with or without the use of a decision support system (DSS) by the attending anaesthesiologist. The purpose of this study was to determine whether using a DSS decreased the time to detect a critic...

J Clin Monit Comput. 2014 Feb;28(1):41-7. doi: 10.1007/s10877-013-9466-1. Epub 2013 Apr 30.

In-home rehabilitation for 6 months improves functional recovery after hip fracture

232 hip fracture patients who had completed initial rehabilitation were randomized to either an in-home rehabilitation program for 6 months (intervention group) or a single session of nutrition education for cardiovascular health with periodic telephone follow-up (control group). The purpose was to compare function between groups after the 6 month ...

JAMA. 2014 Feb 19;311(7):700-8

Ulnar nerve transposition with vascular pedicles prevents the compromise of blood flow

36 patients with cubital tunnel syndrome caused by elbow osteoarthritis were randomized to undergo subcutaneous anterior ulnar nerve transposition with or without preservation of vascular pedicles, to compare the changes in blood flow and clinical results secondary to both treatment options. Results indicated that preserving the vascular pedicles i...

J Hand Surg Am. 2014 Feb;39(2):291-302. doi: 10.1016/j.jhsa.2013.10.029. Epub 2013 Dec 15.

Barbed sutures improve closure times and costs compared to traditional sutures in TKA/THA

34 patients scheduled for primary total knee arthroplasty (TKA) or primary total hip arthroplasty (THA) were randomly allocated to receive barbed or traditional sutures, with the purpose of comparing time to wound closure, cost, and rate of wound complications between suture types. Barbed sutures decreased time to wound closure and improved cost-sa...

J Arthroplasty. 2014 Feb;29(2):283-7. doi: 10.1016/j.arth.2013.05.031. Epub 2013 Nov 22.

Significant differences in shoulder muscle activity during exercise in water vs. on land

16 right-handed participants were randomized to perform 3 elevation movements (flexion, abduction, and scaption) ranging from 0 to 90 degrees at 3 movement speeds (30deg/sec, 45deg/sec, and 90 deg/sec) in water and on land. The purpose of this study was to examine shoulder muscle activation and determine whether there is a difference between dry-la...

J Shoulder Elbow Surg. 2014 Feb;23(2):159-65. doi: 10.1016/j.jse.2013.04.010.

THA: Psoas compartment block associated with reduced pain in immediate post-op period

53 patients undergoing total hip arthroplasty with the anterolateral approach were randomized to receive a psoas compartment block during surgical access in a multimodal postoperative analgesia regimen, or not. Pain, time to request for breakthrough analgesia, and mobility were assessed during the immediate postoperative period. The results indicat...

J Arthroplasty. 2014 Feb;29(2):393-6

Knee OA patients: lateral trunk lean gait walking expends more energy than normal walking

12 patients with medial compartment knee osteoarthritis participated in two treadmill interventions: one session of normal treadmill walking and one session of increased lateral trunk lean walking, in randomized order, to determine the effect of lateral trunk lean gait modification on energy expenditure. Results found that lateral trunk lean walkin...

Osteoarthritis Cartilage. 2014 Feb;22(2):203-9. doi: 10.1016/j.joca.2013.12.003. Epub 2013 Dec 12.

Infrapatellar fat pad excision vs. preservation in minimally invasive TKA

90 patients scheduled to undergo minimally invasive total knee arthroscopy were randomized to infrapatellar fat pad excision or preservation during operation. The purpose of this study was to determine whether removal of the fat pad would affect patella baja, anterior knee pain and functional outcome. Results up to 1 year postoperative indicated no...

Clin Orthop Relat Res. 2014 Feb;472(2):695-701. doi: 10.1007/s11999-013-3321-z.

Local infiltration analgesia comparable in outcome to femoral nerve block after ACLR

60 adult patients scheduled to undergo ACL reconstruction with semitendinosus and gracilis tendon grafts were randomized to receive either local infiltration analgesia (ropivacaine and epinephrine) or a femoral nerve block. The purpose of this study was to determine the efficacies of each treatment with respect to postoperative pain management and ...

Knee Surg Sports Traumatol Arthrosc. 2014 Feb;22(2):317-23. doi: 10.1007/s00167-013-2399-x.

Fewer ligament reconstruction failures with hinged external fixation for knee dislocations

100 patients with a total of 103 knee dislocations were randomized to receive either a hinged knee brace or external fixation with a Compass Knee Hinge as part of a postoperative rehabilitation protocol. This study aimed to determine whether an external fixator would provide equivalent knee range of motion and improve failure rate in comparison to ...

J Bone Joint Surg Am. 2014 Feb 5;96(3):184-91. doi: 10.2106/JBJS.L.01603.

Preoperative autologous blood donation appears unnecessary in non-anaemic patients for TKA

54 patients scheduled for TKA with primary arthritis, Hb levels >120g/L, and ASA I, II, of III were randomized to either preoperative autologous blood donation (PABD) at 14 days, 72 hours preoperatively, or no preoperative blood donation. The purpose of this study was to determine whether PABD was necessary, and if so, whether donation at 14 days p...

Int Orthop. 2014 Feb;38(2):341-6. doi: 10.1007/s00264-013-2185-x.

Alfredson protocol for Achilles tendinopathy: Similar outcome with lower number of reps

28 patients with Achilles tendinopathy were randomized to undergo eccentric heel-drop exercises, following either a do-as-tolerated protocol or the standard Alfredson protocol. The purpose of this study was to compare the two treatment approaches with respect to pain, function and satisfaction after 6 weeks. Results indicated that both study protoc...

J Orthop Sports Phys Ther. 2014 Feb;44(2):59-67. doi: 10.2519/jospt.2014.4720. Epub 2013 Nov 21.

RCT1: Knee in flexion following total knee arthoplasty reduces blood loss and transfusion

180 patients undergoing total knee arthroplasty were randomized to either have their operated knee placed in 120 degrees passive flexion for the first 6 hours postoperatively followed by flexion by placing over a pillow, or to full passive knee extension. The purpose was to determine the impact of keeping the knee in flexion postoperatively on bloo...

Bone Joint J. 2014 Feb;96-B(2):201-9

Comparing a 12-month home exercise program with usual care for post-TKA rehabilitation

108 patients with diagnosed knee osteoarthritis (OA) who had underwent total knee arthroplasty (TKA) were randomized to undergo, beginning 2 months post-surgery, either a 12-month home-based exercise program, or usual care. The purpose of this study was to determine whether this long-term exercise regimen improved pain, disability, quality of life ...

J Rehabil Med. 2014 Jan 30;46(2):166-72. doi: 10.2340/16501977-1242

Rehabilitation in home or community setting more cost-effective than in inpatient setting

29 studies with a total of 6746 patients were included in a systematic review comparing the cost of inpatient rehabilitation with alternative rehabilitation settings, using economic evaluations conducted alongside randomized controlled trials. Furthermore, the least expensive programs were assessed to determine if there were adverse effects on pati...

Arch Phys Med Rehabil. 2014 Jan;95(1):94-116.e4. doi: 10.1016/j.apmr.2013.03.017.

Arthroscopic simulators distinguish between novice and expert orthopaedic trainees

13 studies, consisting of randomized control trials and validation studies, were selected to investigate the role of arthroscopic simulators in improving the surgical skills of users. Systematic review revealed that the simulators discriminated between novice and expert trainees, but not between novice and intermediate trainees on completion time o...

Knee Surg Sports Traumatol Arthrosc. 2014 Jan;22(1):33-40. doi: 10.1007/s00167-012-2228-7. Epub 2012 Oct 2.

Post-meniscectomy medical exercise therapy is beneficial for degenerative meniscal tears

77 patients with an MRI-diagnosed degenerative meniscal tear undergoing arthroscopic partial meniscectomy were randomized to either undergo a 3-month medical exercise therapy (MET) program, or not. The purpose of this study was to examine the effects of this rehabilitation protocol on pain, function and mental health. Results indicated that the MET...

Knee Surg Sports Traumatol Arthrosc. 2014 Jan;22(1):200-6. doi: 10.1007/s00167-012-2354-2. Epub 2012 Dec 23

No significant difference between three manual therapy techniques for chronic neck pain

61 patients with mechanical neck pain were randomized to receive either sustained natural apophyseal glide (SNAG), mobilization, or high-velocity, low-amplitude (HVLA) techniques for manual therapy. The effectiveness of the three techniques were compared in terms of immediate and short-term outcomes of pain, disability, mobility, and the global rat...

Man Ther. 2014 Jan 11. pii: S1356-689X(13)00214-2. doi: 10.1016/j.math.2013.12.002.

Flexed femoral component offers greater postoperative knee flexion in knee arthroplasty

39 patients (40 knees) undergoing primary cruciate-retaining total knee arthroplasty were randomized to receive a femoral component either in a 4° flexion in anterior femoral resection (flexed group) or with neutral resection (0° angle) (control group). The purpose of this study was to determine if postoperative knee flexion was increased in the ...

Knee. 2014 Jan;21(1):257-63. doi: 10.1016/j.knee.2012.10.028. Epub 2012 Nov 24

Similar outcome using intramedullary nailing or plate fixation for distal radius fractures

152 patients with extra-articular distal radius fractures were randomized to have their fracture fixated using either an intramedullary nail, or a volar plate fixation technique. The purpose of this study was to compare the two methods with respect to functional and radiological outcomes. Results at the 2-year follow-up assessment indicated that pa...

Injury. 2014 Jan;45 Suppl 1:S3-8. doi: 10.1016/j.injury.2013.10.045. Epub 2013 Nov 4

Limited evidence on the effects of exercise for improvement of age-related hyperkyphosis

13 studies were evaluated in this systematic review determining whether exercise can improve kyphotic angle in adults at least 45 year old or older with preexisting hyperkyphosis. Measures of kyphosis or forward head posture were investigated, although meta-analysis was not performed due to heterogeneity in intervention techniques. 2 RCTs found sig...

Arch Phys Med Rehabil. 2014 Jan;95(1):129-40. doi: 10.1016/j.apmr.2013.06.022.

High-velocity versus low-velocity training in women with hip osteoarthritis

46 women with various severities of hip osteoarthritis were randomized to undergo an 8-week home-based training program of either high-velocity or low-velocity exercises. The purpose of this study was to determine if high-velocity training offered any advantages over low-velocity training. Physical performance measures, muscle strength, power, thic...

Clin Rehabil. 2014 Jan;28(1):48-58. doi: 10.1177/0269215513492161. Epub 2013 Jul 3

Predictors of treatment response to physical therapy for hip OA remain inconclusive

A secondary analysis was performed using data from a randomized controlled trial (RCT) comparing the efficacy of physical therapy-based interventions for 131 patients with hip osteoarthritis. Patients were randomized into three groups: exercise and manual therapy, exercise therapy alone, or a control group. Potential predictors of treatment respons...

Phys Ther. 2014 Jan;94(1):31-9. doi: 10.2522/ptj.20130173.

Electro-acupuncture reduces arthralgia in cancer patients taking aromatase inhibitors

67 women with non-metastatic breast cancer (Stage I-III) experiencing joint pain attributed to the use of aromatase inhibitor (AI) were included in this study. Subjects were randomized to an intervention group, or a wait list control (WLC) group. Those randomized to the intervention group were further randomly allocated to either electro-acupunctur...

Eur J Cancer. 2014 Jan;50(2):267-76. doi: 10.1016/j.ejca.2013.09.022. Epub 2013 Oct 24

All-inside versus conventional ACL reconstruction: impact on postoperative pain?

46 patients scheduled for anterior cruciate ligament reconstruction were randomized to undergo surgery using either the all-inside technique or conventional technique. The purpose was to compare postoperative pain between the two techniques at 1 month following surgery, and measures of radiographic and functional outcome at 6 months. The results in...

Knee. 2014 Jan;21(1):102-6. doi: 10.1016/j.knee.2013.09.006. Epub 2013 Oct 5

Quadriceps-sparing TKA reduced time to discharge vs standard minimally-invasive approach

102 patients undergoing total knee arthroplasty (TKA) were randomized to receive either a minimally-invasive quadriceps-sparing (MIS) approach or the standard medial parapatellar approach. Clinical, functional and radiological outcomes were compared during the immediate postoperative period and again at 2 years. Results indicated that patients trea...

Knee. 2014 Jan;21(1):189-93. doi: 10.1016/j.knee.2013.07.010. Epub 2013 Aug 2.

Potential improvement in vascularization following rotator cuff repair with L-PRF

20 patients with a chronic full-thickness rotator cuff tear were randomized to undergo arthroscopic repair either with or without the application of leukocyte- and platelet-rich fibrin (L-PRF). The purpose of this study was to determine if L-PRF increased vascularization of the rotator cuff over the first 3 postoperative months. The results at 6 we...

J Shoulder Elbow Surg. 2014 Jan;23(1):3-12. doi: 10.1016/j.jse.2013.08.017

Intra-articular mesenchymal stem cells possibly beneficial for meniscus regeneration

60 patients undergoing a partial meniscectomy were randomized to receive a single postoperative injection of allogeneic human mesenchymal stem cells (50x10^6 or 150x10^6 cell count) or a control vehicle injection of sodium hyaluronate, 7-10 days after surgery. The purpose of this study was to determine if a single intra-articular injection of mesen...

J Bone Joint Surg Am. 2014 Jan 15;96(2):90-8. doi: 10.2106/JBJS.M.00058

Adult stem cells do not appear to accelerate graft-to-bone healing in ACL reconstruction

43 patients undergoing anterior cruciate ligament (ACL) surgery using a hamstring graft were randomly assigned to a stem cell or a control group to evaluate the effect of stem cells on graft-to-bone healing. In the study, adult non-cultivated bone marrow stem cells were harvested from select patients and intra-operatively delivered in and around th...

Knee Surg Sports Traumatol Arthrosc. 2014 Jan;22(1):66-71. doi: 10.1007/s00167-012-2279-9. Epub 2012 Nov 2.

Cementless acetabular component fixation for THA does not differ with or without screws

Five studies (3 RCTs, 1 Cohort, 1 Case-control) were included in this analysis comparing fixation with and without screws in cementless acetabular component in total hip arthroplasty. Studies were included if they provided data on reoperation rates, component migration, or the incidence of osteolysis, as these were the primary outcomes of concern. ...

Int Orthop. 2014 Jan;38(1):7-12. doi: 10.1007/s00264-013-2075-2. Epub 2013 Aug 28

TKA: Patient-specific guides offer no accuracy benefit over conventional instrumentation

128 patients scheduled for total knee arthroplasty were randomized to intervention with either patient-specific guides (PSG) or conventional instrumentation. Participants allocated to PSG were managed with pre-operative planning using either Signature (Biomet Inc.), TruMatch (Depuy Inc.), Visionaire (Smith & Nephew Inc.), or Patient-Specific Instru...

Clin Orthop Relat Res. 2014 Jan;472(1):263-71. doi: 10.1007/s11999-013-2997-4

No effect of topical fibrinogen spray on blood loss and transfusion in TKA

200 patients scheduled for total knee arthroplasty with tourniquet use (inflated prior to incision and deflated before wound closure) were randomized to surgery with or without the application of a fibrinogen topical spray following the cementing of components. Hemostatic parameters of hemoglobin and hematocrit levels, total blood loss, and transfu...

Clin Orthop Relat Res. 2014 Jan;472(1):272-6. doi: 10.1007/s11999-013-3036-1

Adverse effects more frequent with bioabsorbable vs. metal screws in ACL reconstruction

This meta-analysis summarized results from eleven randomized control trials (RCTs) involving 878 randomly allocated patients to investigate the use of bioabsorbable interference screws compared to metal interference screws in single bundle primary anterior cruciate ligament (ACL) reconstruction. The study aimed to report adverse effects and clinica...

Knee Surg Sports Traumatol Arthrosc. 2014 Jan;22(1):142-53. doi: 10.1007/s00167-012-2340-8. Epub 2012 Dec 14.

Mobile bearing yields similar functional outcome as fixed bearing in TKA at two years

352 patients with knee osteoarthritis and scheduled to undergo total knee arthroplasty (TKA) were randomized to receive either a fixed or mobile bearing tibial component. Patients were further randomized to undergo patellar resurfacing or to have the patella retained. The purpose of this study was to compare these implants in terms of clinical outc...

Knee. 2014 Jan;21(1):151-5. doi: 10.1016/j.knee.2013.09.007. Epub 2013 Oct 7

de Quervain tenosynovitis: higher success rates with corticosteroid injection & thumb cast

67 patients with de Quervain tenosynovitis were randomized to receive treatment with a corticosteroid injection (CSI) alone or in combination with thumb spica casting (TSC). The effectiveness of each treatment was examined and compared in terms of success rate, pain intensity, and functional outcomes. Within 3 weeks, both groups experienced signifi...

J Hand Surg Am. 2014 Jan;39(1):37-41. doi: 10.1016/j.jhsa.2013.10.013.

Intraosseous administration of low-dose vanomycin leads to higher tissue concentrations

32 patients scheduled for total knee arthroplasty were randomized to received three different prophylactic antibiotic regimens: intraosseous administration of either 250mg or 500mg vanomycin, or 1g vanomycin administered intravenously. The purpose was to evaluate the effect of intraosseously administered vanomycin in terms of concentrations in subc...

Clin Orthop Relat Res. 2014 Jan;472(1):57-65. doi: 10.1007/s11999-013-3038-z

No significant benefits with computer navigation for THA acetabular component positioning

40 patients undergoing THA were randomized for operation with either a computer-assisted navigation method or the conventional method in the positioning of the acetabular component. One surgeon performed all surgeries. Postoperative CT scans were analyzed to compare the accuracy of both methods. Analysis of the operative anteversion and inclination...

J Arthroplasty. 2014 Jan;29(1):167-71. doi: 10.1016/j.arth.2013.04.017.

Preserving the ligamenta flava as much as possible is beneficial in lumbar microdiscectomy

97 patients with unilateral lumbar disc herniation were randomized to undergo lumbar microdiscectomy using either a traditional (control) or revised (test) technique, which focused on preserving as much of the ligamentum flavum as possible. The purpose of this study was to compare these two surgical approaches with respect to operative time, blood ...

Eur J Orthop Surg Traumatol. 2014 Jan;24(1):23-7. doi: 10.1007/s00590-012-1123-8. Epub 2012 Nov 24

Efficacy of ketamine, pregabalin, and combined analgesia in total hip arthroplasty

142 patients scheduled for total hip arthroplasty were randomized to receive treatment with ketamine infusion during anaesthesia, preoperative oral pregabalin, combined ketamine and pregabalin, or placebo of both. The purpose was to determine if the combination of drugs was more efficacious than either alone. All patients received patient-controlle...

Anaesthesia. 2014 Jan;69(1):46-52

ACLR with lateral plasty may improve lateral compartment laxity in advanced chronic laxity

120 patients with advanced chronic anterior laxity were randomized to receive ACL reconstruction (ACLR) with or without extra-articular ilio-tibial band tenodesis. The study aimed to examine ACLR outcomes and objective laxity when combined with lateral plasty. After 2 years, patients who underwent ACLR with lateral plasty experienced a greater impr...

Knee. 2014 Jan;21(1):58-65. doi: 10.1016/j.knee.2013.06.001.

Effect of arthroscopic simulator on operating room performance remains inconclusive

This systematic review analyzed 19 studies involving 465 participants with varying degrees of orthopaedic experience, to determine whether arthroscopic simulators improve simulator and operative technical skills. Common arthroscopic tasks assessed in these studies included throwing a suture, probing, hook manipulation, and shaving/burning. An analy...

Arthroscopy. 2014 Jan;30(1):121-33. doi: 10.1016/j.arthro.2013.09.084. Epub 2013 Nov 28.

The Chaos Clinic Falls Prevention Program effective for reducing falls in elderly patients

1314 patients (>70 years of age) were recruited to investigate the effect of the Chaos Clinic Falls Prevention Programme on fall prevention in older patients. Participants were randomized to either the Chaos Clinic Falls Prevention Programme or to a control intervention (general injury prevention brochure). Follow-up was conducted over 1 year, and ...

Injury. 2014 Jan;45(1):265-71. doi: 10.1016/j.injury.2013.03.010. Epub 2013 Apr 8

Knee aspiration provides only short-term benefits in the treatment of knee effusion

One hundred and sixty seven patients with acute knee joint effusion were randomized to either undergo knee aspiration or not, to determine whether this intervention is effective in improving clinical and functional outcomes. Results indicated that pain, edema, range of motion, analgesia intake, and knee function scores were significantly improved w...

Knee Surg Sports Traumatol Arthrosc. 2014 Jan;22(1):226-32. doi: 10.1007/s00167-013-2379-1. Epub 2013 Jan 19

Early motion vs. immobilization post-arthroscopic rotator cuff repair show similar outcome

One hundred and twenty four patients (under 65 years of age) with small to medium cuff tears undergoing arthroscopic rotator cuff repair were randomized to receive rehabilitation involving either early passive motion or immobilization. Pain relief, functional outcomes, and shoulder ultrasounds were assessed to determine the most effective protocol....

J Bone Joint Surg Am. 2014 Jan 1;96(1):11-9. doi: 10.2106/JBJS.M.00034.

Gamma nail more effective than sliding hip screw in unstable intertrochanteric fractures

Eighty patients with a 31-A2.2 or A2.3 AO/OTA multifragmentary intertrochanteric fracture were randomized to receive either a Gamma intramedullary nail or an AMBI sliding hip screw. Parker mobility, Barthel Index, and EuroQol-5D quality of life scores were primary outcomes. After 12 months, patients treated with a Gamma nail achieved higher outcome...

Int Orthop. 2014 Jan;38(1):155-61. doi: 10.1007/s00264-013-2196-7.

Similar outcome whether tourniquet was used throughout TKA or during cementation only

Seventy-one patients (79 knees) undergoing total knee arthroplasty (TKA) were randomized to either have the tourniquet inflated throughout the procedure or during the cementation phase only. The purpose of this study was to compare the two protocols with respect to operative time, blood loss, as well as postoperative clinical and functional outcome...

Clin Orthop Relat Res. 2014 Jan;472(1):169-74. doi: 10.1007/s11999-013-3124-2.

Custom cutting blocks vs conventional instrumentation in total knee arthroplasty

Eighty patients scheduled for primary total knee arthroplasty were randomized to instrumentation with custom cutting blocks or to conventional intramedullary and extramedullary instrumentation. Intraoperative data concerning operative time and blood loss were collected, and radiographic outcome was analyzed at 6 weeks postoperatively. The results i...

Knee. 2014 Jan;21(1):185-8. doi: 10.1016/j.knee.2013.08.003. Epub 2013 Aug 15

Pilot trial comparing accelerated and standard surgical care for hip fractures

Sixty patients with hip fractures were randomized to undergo surgical treatment using either an accelerated or the standard treatment protocol, in order to assess the feasibility of a true randomized controlled trial comparing these two approaches. Overall, feasibility targets were attained, with 60 patients recruited in less than 18 months, over 7...

CMAJ. 2014 Jan 7;186(1):E52-60. doi: 10.1503/cmaj.130901. Epub 2013 Nov 18

Surgical repair VS acromioplasty and physiotherapy in non-traumatic rotator cuff tear

Patients (180 shoulders) above 55 years of age with non-traumatic supraspinatus tears were analyzed one year post-intervention to determine if rotator cuff repair is superior to alternative treatment approaches. Patients were randomly allocated to a physiotherapy group, acromioplasty and physiotherapy group, or rotator cuff repair, acromioplasty an...

Bone Joint J. 2014 Jan;96-B(1):75-81. doi: 10.1302/0301-620X.96B1.32168.

Eicosapentaenoic and docosahexaenoic acid supplementation in breast cancer patients

38 postmenopausal women being treated with aromatase inhibitors for breast cancer were randomized in this trial to determine the effect of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on bone turnover and resorption. Participants were treated with capsules of either EPA+DHA or placebo (7 capsules/day) for 3 months, after which they we...

Nutr Cancer. 2014;66(1):68-76. doi: 10.1080/01635581.2014.847964. Epub 2013 Nov 25

Draw-back technique safe and effective in slip reduction for isthmic spondylolisthesis

94 adult patients with isthmic spondylolisthesis were randomized to be treated with either conventional in situ posterior lumbar interbody fusion (PLIF) or a draw-back technique, using pedicle screws to reduce vertebral slippage, combined with PLIF. The purpose was to determine the effect of slipped verterbrae reduction on clinical outcomes, radiog...

Eur Spine J. 2014 Jan;23(1):172-9. doi: 10.1007/s00586-013-2858-6. Epub 2013 Jun 14

Five-year follow-up of the effects of calcium supplementation in postmenopausal women

This investigation is a continuation of the 5 year Auckland calcium study, which randomly allocated healthy, post-menopausal women into a calcium or placebo group to compare fracture incidence, bone mineral density (BMD), and cardiovascular end-points between groups. The purpose of this extended follow-up was to investigate the post-trial effects o...

Osteoporos Int. 2014 Jan;25(1):297-304. doi: 10.1007/s00198-013-2526-z. Epub 2013 Oct 10.

Patient sense of coherence may play an important role in hip fracture rehabilitation

45 patients with a history of hip fracture were randomized to undergo either a 12-week individualized, progressive resistance training program or no intervention at all. The purpose of this secondary analysis was to examine the effect a patients sense of coherence (SOC) has on functional outcome upon completion of the intervention. Results indicate...

J Aging Phys Act. 2014 Jan;22(1):138-45. doi: 10.1123/japa.2012-0229. Epub 2013 Mar 26

Oral ibandronic acid inferior to IV zoledronic acid for metastatic breast cancer to bone

1404 patients with bone metastases from breast cancer were randomized to receive treatment with either oral ibandronic acid or intravenous zoledronic acid. The frequency and timing of skeletal-related events (SREs) was the primary non-inferiority endpoint. After 96 weeks of treatment, 50 mg of oral ibandronic acid given daily was inferior to 4 mg o...

Lancet Oncol. 2014 Jan;15(1):114-22. doi: 10.1016/S1470-2045(13)70539-4.

Home-based strength and stretching exercises for chronic neck pain yield similar outcomes

57 female patients with chronic neck pain were randomized to undergo either a home-based strength exercise program or stretching exercise program for one-year. The two interventions were compared with respect to changes in neck pain intensity and function. No significant difference was found in either neck pain intensity or function between the tre...

BMC Musculoskelet Disord. 2014 Jan 8;15(1):6. doi: 10.1186/1471-2474-15-6

Internal fixation VS hemiarthroplasty for hip fractures produce similar outcomes at 6 yrs

To determine the long term efficacy of surgical hip fracture techniques, 222 patients with displaced intracapsular femoral neck fractures were randomly allocated to undergo either hemiarthroplasty or internal fixation. Outcomes including patient pain, hip function, quality of life, survival, and frequency of re-operation were measured for a minimum...

Clin Orthop Relat Res. 2014 Jan;472(1):360-7. doi: 10.1007/s11999-013-3245-7. Epub 2013 Aug 24.

Clinical prediction rule for lumbar stabilization exercise could not be validated for LBP

105 patients with low back pain (LBP) were randomized to receive treatment with either lumbar stabilization exercises (LSE) or manual therapy (MT). A clinical prediction rule (CPR) predicting successful outcomes based on CPR status following LSE was tested for validity. After 8 weeks, the present study was unable to validate CPR, as the interaction...

J Orthop Sports Phys Ther. 2014 Jan;44(1):6-B13. doi: 10.2519/jospt.2014.4888.

Core stabilization in patients with arm injury may prevent compensatory movement patterns

27 patients with elbow and wrist disorders were randomized to undergo traditional arm rehabilitation with or without core stabilization exercises. The purpose of this study was to determine whether a core stabilization program is effective in preventing compensatory movement patterns and improving physical function. Results indicated that stabiliza...

Clin Rehabil. 2014 Jan;28(1):36-47. doi: 10.1177/0269215513492443. Epub 2013 Jul 3.

Improvement in LBP and quality of life with Pilates in patients with HTLV-1 virus

22 patients with chronic low back pain associated with human T-lymphotropic virus type 1 were randomized in this crossover study to determine the effect of Pilate method intervention. Participants were allocated to treatment through 15 weeks of Pilates followed by 15 weeks of control intervention (normal activity), or vice versa. The results indica...

J Bodyw Mov Ther. 2014 Jan;18(1):68-74. doi: 10.1016/j.jbmt.2013.05.010. Epub 2013 Jun 5

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